About Us

Philosophy & Mission

Brai3n's research philosophy closely follows Albert Einstein’s philosophy:

“The grand aim of all science is to cover the greatest number of empirical facts by logical deduction from the smallest number of hypotheses or axioms” 

Thus its philosophy is to develop novel neuromodulation treatments by investigating the common neurophysiological mechanisms that cluster into groups of pathologies, namely the thalamocortical dysrhythmias (tinnitus, pain, slow wave epilepsy, Parkinson’s disease and depression) and reward deficiency syndromes (obesity, addiction, OCD).

A new line of research will aim to develop new neuromodulation techniques for the study and treatment of disorders of global and self-consciousness, as a logical extension of the work on sensory consciousness (phantom percepts).

The scope and extent of the research program of Brai3n is both its weakness and strength. Success can only be guaranteed by an extensive collaboration with basic neuroscience researchers, engineers, functional neuroimaging experts and clinicians from non-neurosurgical fields.

In addition, close contact with neurophilosophers, both in Belgium and Dunedin, and moral philosophers will help to guide the translation of the accumulated basic neuroscientific data into novel clinical applications.


BRAI3N is an international research group that follows the same philosophy and has the same mission. The same research techniques, the same software (Win EEG, sLORETA,…) and hardware (EEG, tES etc), the same normative databases and the same methodology  will be used so that data are comparable and can be pooled if necessary. In order to be complementary each partner is focusing on a specific part of the common research topics: Belgium will perform advanced clinical trials, New Zealand predominantly translational and USA experimental small group trials and group data analyses.

All centers will continue to focus on tinnitus, but each center will also add other pathology from the same 2 groups of pathologies (thalamocortical dysrhythmia and reward deficiency): Antwerp pain (fibromyalgia, whiplash and neuropathic pain), Dunedin reward deficiency pathology (obesity, addiction) as well as cognitive decline and stroke and Dallas hearing loss, stroke, traumatic brain injury.